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Hormone Replacement Therapy
Philip Borgardt MD, FACP
Hormones

 

DHEA

DHEA is produced by the adrenal glands.  DHEA begins to drop when we are thirty years old and declines linearly until we die.  In fact, death ensues as soon as the DHEA levels hit zero.  Some people, therefore, use DHEA levels as a biomarker for aging.  DHEA plays a critical role in lowering our cholesterol, keeping our hearts healthy, minimizing fat deposition, preventing the development of diabetes, arthritis and senility. Dr. Borgardt uses DHEA as an essential part of our  treatment program and  monitors DHEA sulfate levels to assure optimal blood DHEA levels.

Benefits of DHEA

  • Lowers blood cholesterol
  • Improves heart health
  • Slows onset or progression of diabetes
  • Favorably impacts arthritis
  • Reverses declining mental acuity 

Estrogen

Estrogen is an essential sex hormone that declines abruptly in women during their menopause.  When women do not initiate a prompt estrogen replacement program at the time of menopause, they undergo accelerated aging manifested by: osteoporosis, risk of senility, heart disease, loss of muscle mass, loss of skin elasticity and thickness, atrophy of the female genitalia, and mood changes. Estrogen replacement therapy significantly delays or prevents this accelerated aging process seen in women following menopause.  In fact, women who take estrogen replacement have half the degenerative diseases of women who do not take estrogen replacement and live an average of 3.5 years longer.  What is even more amazing, is that these positive statistics are with those patients on Premarin(non-human estrogen taken from the urine of pregnant horses).  Dr. Borgardt uses only natural estrogen replacement which has been shown to be safer than Premarin  He measures estradiol levels and adjusts dosages to pre-menopausal levels.  We have every reason to believe that the anti-aging effects of natural human estrogen will be even better than with horse estrogen, but without the side effects.

 Benefits of Estrogen

  • Relieves menopausal symptoms
  • Increases female life expectancy
  • Protects against coronary artery disease
  • Boosts brain function
  • Helps prevent osteoporosis and fractures
  • Protects against Alzheimer's disease
  • Improves skin and muscle quality

Human Growth Hormone

In 1994, The FDA authorized the use of Human Growth Hormone for adults.  For the first time, adults are now able to have their age-related deficiency of this critical hormone replaced safely with natural, pharmaceutically produced Human Growth Hormone.  The results or HGH replacement are astounding.

Studies have shown that Biomarkers of Aging ( strength, reaction time, skin elasticity, vital capacity, tactile senses and others) can be improved.  Patients may experience 1% gain in lean muscle mass per month and 2% loss of body fat per month.  Skin wrinkles and age spots can be improved.  Sexual vitality may return.  We anticipate that with HGH replacement along with other indicated hormone replacement including nutrition and exercise, that we can now expect to live in excellent health.

 Benefits of HGH

  • Increases bone mass
  • Increases exercise performance
  • Improves skin elasticity
  • Enhances sexual performance
  • Improves quality of sleep
  • Lowers blood pressure
  • Thickens skin
  • Decreases sick days
  • Helps the body heal faster
  • Strengthens bones
  • Improves kidney function
  • Boosts energy to youthful levels
  • Improves quality of life
  • Lowers lipid levels
  • Speeds recovery in heart patients
        • Loses weight, gains muscle

        • Improves congestive heart failure

        Melatonin

        Melatonin is produced by the pineal gland and is stimulated by darkness,  This is why we have a pulse on melatonin release several hours after sundown.  Melatonin plays a crucial role in restful, restorative sleep, regulating our 24 hour sleep-awake cycle, and in facilitating our immune system.  Studies have shown that melatonin increased the lifespan of mice by 25%.  Similar studies have shown melatonin to reduce the risk of breast cancer in mice.  Melatonin may also decrease the chance of other cancers such as prostate cancer in males.  Melatonin is an extremely powerful antioxidant that is able to enter the mitochondria of cells and neutralize free radicals.

        Benefits of Melatonin

        • Restores youthful sleep patterns
        • Effectively treats jet lag
        • Boosts immune system
        • May have anti-cancer effects

        Pregnenolone "The Smart Hormone"
        Pregnenolone is produced from cholesterol and is the "grandmother hormone" of all steroid hormones in the body.  Pregnenolone acts as a precursor to our essential steroid hormones such as DHEA, testosterone, estrogen, glucocorticoids, mineralocorticoid and therefore an ample supply is critical.  We have seen deficiencies in the above hormones normalize just by adding Pregnenolone to the treatment regime.

        Pregnenolone also has significant direct effects.  It is extremely important for optimal mental performance and is synthesized the supporting neuronal cells in the brain.  Studies have shown that when Pregnenolone is administered, memory is enhanced and mood is improved.  Pregnenolone has nerve growth factor ability and has been used is spinal cord injury patients.  Dr. Borgardt uses Pregnenolone as a essential part of its supplement program.

        Benefits of Pregnenolone

        • Precursor of many other hormones
        • Fights the effects of fatigue and stress
        • Relieves arthritis pain
        • Improves heart disease
        • Boosts the immune system
        • Protects against coronary artery disease
        • Improves mood and memory
        • Essential to full brain function
        • Protects against Alzheimer's disease


        Progesterone
        Progesterone is also a female sex hormone that keeps estrogen in balance and is therefore absolutely necessary in the female hormone replacement program regardless of whether the female has a uterus or not.  This concept is not understood buy some physicians and this has lead to an increase in cancers of the uterus and breast in women on estrogen replacement, alone.  Progesterone has powerful anti-cancer properties.  In addition, progesterone facilitates the action of other hormones such as thyroid, testosterone, and endorphins.  Synthetic progesterone (progestin) such as Provera lack many of the beneficial properties of Progesterone and in fact actually serve to increase LDL "the bad form of cholesterol".  Provera also does not have the beneficial effect that Progesterone has in increasing bone mass, reversing osteoporosis, and burning fat.  Prover has been shown to increse the risk of breast cancer while Bio-Identical progesterone has been shown to decrease the risk of breast cance.  Dr. Borgardt uses natural progesterone replacement in his female HRT program as indicated by the individual blood levels and symptoms.

        Benefits of Progesterone

        • Natural antidepressant and tranquilizer
        • Improves female libido
        • Protects against cancer
        • Boosts thyroid action
        • Helps the body use fat rather that store it
        • Helps prevent osteoporosis

        Testosterone

        Both men and women need testosterone for optimal health.  Testosterone is needed for libido, muscle. leanness, and sense of well being.  Menopausal women have low to non-detectable testosterone levels with resultant loss of libido and increase in body fat.  Return of libido and improved mood return within days of testosterone replacement by transdermal cream.   Regrowth of muscle and bone can occur within months and is facilitated by a weight resistance training program.

        The testosterone level in males peaks at age 17 and declines 1% per year thereafter.  A middle-aged male can therefore have a testosterone level 40% below his peak in sex binding globulins, which make the lowered testosterone that is present even less effective.  Loss of testosterone in males leads to atherosclerosis and heart attacks, obesity, fatigue, depression, anxiety, and increased mortality.

        These symptoms come on long before the male loses his sex drive or becomes impotent.  There is no evidence that testosterone replacement therapy in males causes prostate cancer or prostate enlargement.  In fact, some Urologists-Oncologists say that testosterone may decrease the incidence of prostatic hypertrophy and prostate cancer.  Dr. Borgardt uses topical testosterone replacement as an essential part of its Hormone Replacement Therapy (HRT) program for both men and women based on the patient's total and free testosterone levels and their levels of sex binding globulins.

        Benefits of Testosterone:

        • Boosts male and female libido
        • Facilitates a healthy heart
        • Helps prevent osteoporosis
        • Fights fat
        • Increases muscle strength and improves appearance
        • Increases energy and vitality
        • Increases aerobic activity
        • Increases muscle mass
        • Improves sense of well being and mood
        • Decreases body fat
        • Thickens skin
        • Imroves sleep
        • Decreases cardiovascular risk
        • Effects can be equivalent of reversing 10 years of aging


        Side effects of low testosterone:

        • Fatigue
        • Loss of muscle strength
        • Reduced libido
        • Osteoporosis
        • Heart disease
        • Irritability
        • Insomnia
        • Erectile dysfunction
        • Prostate problems
        • Low sperm count
        • Depression.anxiety
        • Reduced muscle mass
        • Memory impairment
        • Impaired blood cell formation
        • Reduced cognitive function

        Testosterone References:
        Carter HB, Pearson JD, Metter EJ, Chan DW, Andres R, Fozard JL, Rosner W, Walsh PC.  PRostate 1995 Jul;27 (1): 25-31.  Longitudinal evaluation of serum androgen levels in men and without prostate cancer.  There was no correlation of serum testosterone or free testosterone with prostate cancer.

        Cooper CS, Macintosh JH, Perry PJ, Yates WR, Williams RD.J Urol 1996 AUg;156 (2Pr1):438-41; Discussion 441-2.  The effect of exogenous testosterone on total and free prostate specific antigen levels in healthy young men.  There was no increase in PSA when supplemental testosterone was used.


        Thyroid

        Thyroid hormone is essential for life.  Proper thyroid levels are needed for optimal functioning.  Conventional medicine replaces thyroid only when indirect laboratory measurements indicate that it is low.  We preform more elaborate thyroid testing including measuring the free thyroid hormone, which is the active hormone available to the cells in our body.  In addition, we also carefully measure the basal body temperature which is the ultimate indicator of whether we are hyper or hypothyroid.  Many times, replacement of human growth hormone or testosterone to more youthful levels creates a greater need for thyroid hormone.  In these cases, we add thyroid hormone replacement to our regime.

        Benefits of Thyroid:

        • Controls cell growth and metabolism
        • Helps with weight maintenance
        • Improves heart and vascular health
        • Renews energy
        • Improves concentration
        • Regulates body temperature

           

                               188 Tank Farm Road  San Luis Obispo, CA 93401  805-540-5544
                                                                                          2010  Copyright  Philip Borgardt MD, FACP

        NO PRESCRIPTION WILL BE PROVIDED UNLESS A CLINICAL NEED EXISTS BASED ON REQUIRED LAB WORK, PHYSICIAN CONSULTATION AND CURRENT MEDICAL HISTORY, EITHER THROUGH PATIENT'S PERSONAL PHYSICIAN OR DR. BORGARDT.  PLEASE NOTE, AGREEING TO LAB WORK DOES NOT AUTOMATICALLY EQUATE TO CLINICAL NECESSITY AND A PRESCRIPTION.
        No claim or opinion on this web site is intended to be, or should be construed to be, medical advice.  Please consult with a healthcare professional before starting any therapeutic program.

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